Selected Nemeth Publications

Nemeth MJ, Topol L, Anderson SM, Yang Y, and Bodine DM. Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proc Natl Acad Sci 104, 15436-15441, 2007

Nemeth MJ and Bodine DM. Regulation of hematopoietic stem cells by Wnt signaling pathways. Cell Res, 17, 746-58, 2007.

Nemeth MJ, Kirby MR, and Bodine DM. Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation. Proc Natl Acad Sci 103, 13783-13788, 2006.

Nemeth MJ, Cline AP, Anderson SM, Garrett-Beal LJ, and Bodine DM. Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood 105, 627-634, 2005.

Nemeth MJ and Lowrey CH. An erythroid-specific chromatin opening element increases beta-globin gene expression from integrated retroviral gene transfer vectors. Gene Ther Mol Biol 8, 475-486, 2004.

Pal S, Nemeth MJ, Bodine D, Miller JL, Svaren J, Thein SL, Lowry PJ, and Bresnick EH. Neurokinin-B transcription in erythroid cells: Direct activation by the hematopoietic transcription factor GATA-1. J Biol Chem 279, 31348-31356, 2004.

Nemeth MJ, Curtis DJ, Kirby MR, Garrett-Beal LJ, Seidel NE, Cline AP, and Bodine DM. Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood 102, 1298-1306, 2003

Kitareewan S, Pitha-Rowe I, Sekula D, Lowrey CH, Nemeth MJ, Golub TR, Freemantle SJ, and Dmitrovsky E. UBE1L is a retinoid target that degrades PML/RAR and triggers apoptosis in acute promyelocytic leukemia. Proc. Natl. Acad. Sci. 99, 3806-3811, 2002

Nemeth MJ, Bodine DM, Garrett, LJ, and Lowrey CH. An erythroid-specific chromatin opening element remodels -globin promoter chromatin structure and increases gene expression. Blood Cells Mol. Dis. 27 , 767-780, 2001.

McInerney JM, Nemeth MJ, and Lowrey, CH. Slow and steady wins the race? Progress in the development of vectors for gene therapy of -thalassemia and sickle cell disease. Hematology 4, 437-455, 2000.

Iler N, Goodwin AJ, McInerney J, Nemeth MJ, Pomerantz O, Layon ME, and Lowrey CH. Targeted remodeling of human beta-globin promoter chromatin structure produces increased expression and decreased silencing. Blood Cells Mol. Dis. 25, 47-60, 1999.