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Equipment
RPCI NMR Equipment:
Brüker AMX-400:
This is a four channel instrument, but it does not have gradients. There are five probes available for use on the 400: A 1H selective probe, a triple resonance probe for 13C or 31P observe and 1H decoupling, a gradient capable inverse probe for 1H observe and 13C or 15N decoupling, a 19F probe with 1H decoupling and a 10mm BB probe suitable for most X nuclei.
Varian INOVA 600:
The INOVA is fully gradient capable three channel instrument. It is equipled with two probes, an inverse probe for 1H observe and 13C or 15N decoupling. This probe is quite useful for working with proteins and DNA. 
It is also equiped with a Capillary Flow probe for volume limited samples (uses ~10 uL/samples). This is the probe we use most of the time.To go along with the flow probe we have a Leap Technologies PAL liquid sample handler to allow higher throughput and automation. This can be used with microvials as seen here or with 96 well plates.
Our agreement with the University at Buffalo regarding the joint operation of the NMR Resource with the UB NMR facility enables RPCI researchers to also access The following instrumentation:
AT UB: VARIAN spectrometers operated at UB (750, 600, 2*500, 400 and 300 MHz); the 750 and 600 MHz spectrometers are equipped with cryogenic probes, and one of the 500 MHz spectrometers is equipped with a nanoprobe for acquiring NMR spectra under ‘magic angle spinning’ (MAS).
AT the NY Structural Biology Center: (900, 3*800, 700, 600, 500 MHz), all of which are equipped with cryogenic probes.
To go along with the flow probe we have a Leap Technologies PAL liquid sample handler to allow higher throughput and automation. This can be used with microvials as seen here or with 96 well plates.
